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PDE-4, phosphodiesterase-4

Molson Coors Brewing company is in a joint venture with Hexo Corp to develop cannabis-based drinks for the Canadian market, while Lagunitas, a craft beer owned by Heineken, has launched HiFi Hops, a beer flavored sparkling water that contains both CBD and THC

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Rolipram, a phosphodiesterase-4 inhibitor, indirectly enhances proteasome activity by increasing cAMP levels and reduces tau aggregation in AD models