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Semaglutide belongs to a broader class of medications known as GLP-1 receptor agonists, which are used to treat obesity and type 2 diabetes." Semaglutides act like the glucagon-like peptide-1 (GLP-1) hormone our bodies make, which is released from our gut after we eat, explains Jessica Duncan, MD, DABOM, DABA, chief medical officer at Ivim Health

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Also, if you regularly take NSAIDs for joint pain, it might increase kidney markers, regardless of any medication effects