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Safety notes: Contraindicated in pregnancy, breastfeeding, active malignancy, poorly controlled diabetes, and untreated hypothyroidism

Whyte HJ, Baughman RD

Predicted physicochemical properties supported its hydrophobic character and oral bioavailability, suggesting it is a metabolically stable and BBB-permeable molecule [1]

Modern clinical practice is aimed at frequent measurement of disease activity using validated measures like the SLE Disease Activity Index (SLEDAI) or the British Isles Lupus Assessment Group (BILAG) scores

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