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Research indicates that low maternal B12 status is associated with a higher risk of adverse outcomes, including neural tube defects, preterm birth, low birth weight and potential impacts on cognitive development, although evidence of direct causation remains limited

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For a quality oral option, BPC Rapid Pro is our recommended pick, a higher-concentration capsule backed by InfiniWell's published quality standards and third-party testing

Answering yes to these questions gives the findings far more weight than isolated case reports or marketing-driven claims

An especially sensitive event that relies on a sufficient amount of folate is the closure of the neural tube, the precursor to the brain and spinal cord