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Biol Psychiatry 1993
"Metabolic effects of tesamorelin, a growth hormone-releasing factor, in patients with HIV-associated abdominal fat accumulation: a randomized, double-blind, placebo-controlled trial." HIV Medicine , 11(5), 331340
Age-Related Decline In the body, GHK-Cu naturally occurs at concentrations of approximately 200 ng/mL in plasma at age 20, but these levels decline progressively with age to less than 80 ng/mL by age 60 - this age-related decline correlates with decreased tissue repair capacity, skin aging, and impaired regenerative responses, leading to the hypothesis that GHK-Cu decline contributes to aging phenotypes and that restoration of youthful levels through supplementation could have anti-aging benefits
Risrus et al
Together, these delivery-centered strategies provide the mechanistic context needed to revisit exposure levels that were previously precluded by toxicity
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