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Randomization and masking Randomization (1:1) to semaglutide 2.4 mg or placebo was done centrally by the clinical research organization (Parexel) in a double-blind manner using an interactive web-based response system (IWRS) with a fixed-size blocking schema, without stratification
doi: 10.1056/NEJMoa030204
Research-use positioning helps separate educational content from medical, supplement, treatment, recovery, or performance guidance
What MRP with DRGs includes: Allied health services Pharmaceuticals Diagnostic tests Medical and nursing staff Equipment use Indirect costs Medical and surgical procedures What it excludes (handled separately): Selected high-cost medications Selected high-cost prostheses and implants How it works: The MRP is determined using the Australian Refined Diagnosis Related Groups (AR-DRGs) classification, which analyzes claims charges and resource weights
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