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Researchers are also studying how these medications may shift the gut microbiome, including bacteria such as Akkermansia muciniphila

HistaminX features plant-derived compounds like quercetin, luteolin, and rutin

However, most research is conducted on six months trials which suggests that it can be taken for up to six months

For RCTs, this included assessment of: (1) risk of bias (via Cochrane RoB 2 tool), (2) inconsistency of results across studies, (3) indirectness of evidence, (4) imprecision due to sample size or confidence intervals, and (5) potential publication bias

However, the effects of these interventions on MASLD or ALD remain uncertain