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Statements Author contributions PS: Conceptualization, Data curation, Funding acquisition, Investigation, Visualization, Writing original draft, Writing review & editing

Some people describe the appetite suppression as "wider" on retatrutide, affecting not just hunger but food preoccupation and cravings in a way that feels broader than tirzepatide

Hyperthyroidism, which occurs when the thyroid produces higher levels of hormones

Appetite Suppression: Consistent with the MC4R agonism, a noticeable reduction in appetite and food cravings is common, which may lead to weight loss over longer research cycles

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