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Given its numerous functions, low levels of thiamine can lead to reduced energy production due to impaired mitochondrial function, which damages neurons, and cells that have high energy demands, making them particularly vulnerable to potential damage or cell death (40)

As a cofactor for the enzyme aromatic L-amino acid decarboxylase, pyridoxine is directly involved in converting 5-hydroxytryptophan to serotonin

Hypoglycemia in 42%, tonsillar hypertrophy in 15%, intracranial hypertension in 3 subjects

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