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Listening to the heart and measuring the rate and rhythm of the heartbeat, listening for heart murmurs, checking for swelling in the feet, and taking the pulse can all aid in the diagnosis of arrhythmias (NHLBI 2011a)

These limitations may partially explain the discrepancy between promising preclinical results and the limited success observed in clinical trials

[19] Epitalon appears to increase the proliferation of lymphocytes in the thymus, putatively increasing production of interferon gamma by T-cells

Albeit the limitation of the in vitro studies with a single OCCC cell line, we believe that the levels of cysteine and other thiols would be even higher in patients with this histological type compared to OSC, allowing faster disease progression and recurrence

Sulfasalazine acts as a competitive inhibitor of SLC7A11 by interacting with the backbone of TM1a and R396 as well as Y240, Y244, and Y444 of SLC7A11 [203]