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A 2012 analysis by Pickart and Margolina published in BioMed Research International identified GHK-Cu as a regulator of at least 4,000 human genes, including upregulation of collagen I, collagen III, and decorin, alongside downregulation of metalloproteinases MMP-1 and MMP-2 under certain conditions [5]

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Now, exploiting lipid peroxidation process for regulation of ferroptosis has been purported to be a favourable approach especially for the management of chemorefractory and metabolically active tumours [84, 85]