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[7] This is why the two are frequently studied as complementary rather than competing mechanisms: the entire rationale for the CagriSema combination is that pairing an amylin analog (cagrilintide) with a GLP-1 analog (semaglutide) engages two different hormone systems together

There are also more serious risks to consider, such as pancreatitis, gallbladder problems, kidney issues, thyroid tumors, and severe gastrointestinal conditions

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10.1016/S0140-6736(83)91628-8 81