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Consistent with the previously demonstrated ability of fluorescently-labelled GIP to access and activate the AP 5,7 , we found that acyl-GIP increased the total number of cells in the AP staining positive for cFos (a marker of neuronal activation) in control mice

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ID8 Trp53 / model of ovarian cancer For the ovarian cancer experiments, C57BL/6J female mice (67 weeks old) were purchased from Charles River Laboratories UK (RRID: IMSR_JAX:000664) and allowed to acclimatize for at least 1 week before any regulated procedures were performed