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those of healthy younger subjects ( Red Blood Cell Transfusion and ATP The widely reproduced finding that restrictive RBC transfusion is non-inferior to liberal RBC transfusion in patients with anemia, taken together with the finding that anemia itself is a strong risk factor for poor outcomes, suggests that there is potential for improved approaches to RBC storage in anticipation of transfusion ( 2 delivery but also O 2 consumption by the tissues ( 2 delivery does not necessarily result in a net improvement in organ function in vulnerable patients, possibly reflecting storage-induced loss of the regulation of O 2 delivery distribution

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