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Without enough B12, red blood cells can become large and irregular (megaloblastic anemia), which reduces their ability to carry oxygen efficiently

However, a later analysis looking specifically at patients with early ALS those within one year from symptom onset revealed that those given methylcobalamin had a significantly slower progression compared with those on a placebo

But, some patients might need more frequent doses

This sensitive area may also appear slightly red

This distinguishes it from GLP-1 medications, which in some patients have been associated with significant lean mass reduction alongside fat loss