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Studies examining the effects of GLP-1 receptor agonists on neural reward reactivity tend to report more consistent findings for acute rather than long-term administration, possibly due to neural adaptations with long-term exposure [39]
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Liu Y, Liu H, Meyer C, Li J, Nadalin S, Konigsrainer A, Weng H, Dooley S, Ten DP (2013) Transforming growth factor- (TGF-)-mediated connective tissue growth factor (CTGF) expression in hepatic stellate cells requires Stat3 signaling activation
Cells seeded at 8000 per well in 24-well plates (with three replicates per treatment) were treated with semaglutide for 24 h and then harvested and homogenized in 500 L of assay buffer on ice for 1 h
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