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JAMA Cardiol (2021) 6(8):92635

PDE5 inhibitors usually take 3060 minutes to work, but their effectiveness can be influenced by food intake and metabolic variability

NOC billing requires the drug name, strength, dosage administered, and manufacturer to appear in the claim narrative or CMS-1500 Box 19

Even with weekly injections for a full year, the cumulative weekly B6 dose from the compound alone ranges from 5 to 10 mg, far below the levels associated with neuropathy