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Oxidative stress is classically defined as a redox imbalance in which there is an excess formation of oxidants or a decrease in amount of function of antioxidants (3)

40,41 Complementary mouse studies extended these findings, demonstrating that reactive astrocytes, characterized by hypertrophy and elevated MAOB expression, produced excessive tonic GABA inhibition, impairing fear extinction retrieval (Study 4)

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