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Their combined effect, however, has not been clinically studied

Utilizing this system, we interrogated the influence of environmental factors on acetaminophen toxicity which has proven difficult in vertebrate models due to cost and inter-individual variability

Ikonen, E

Proteostasis in cardiovascular health and disease Cardiovascular tissues, particularly the heart, operate under constant mechanical, metabolic and oxidative stress and therefore depend critically on robust proteostasis to sustain contractile function, bioenergetic efficiency and cellular survival