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Description

Bone marrow mesenchymal stem cell-derived exosomes miR-367-3p, in Erastin-induced BV2 cells, targets the binding enhancer of zeste homolog 2 (EZH2), inhibiting its expression

The only placebo-controlled trial (Zubair et al., 2016) used 1,200 mg twice weekly for 6 weeks, showing only 37.5% completion rate versus 18.7% placebo, with benefits fading by 6 months