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Furthermore, achieving therapeutic concentrations of metabolites solely through diet is difficult, and rigorous adherence to strict dietary protocols (like CR or IF) is challenging for patients with MI, particularly those with comorbidities such as diabetes or frailty

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The presence of Vitamin C in the digestive tract and bloodstream protects quercetin from rapid oxidation, significantly enhancing its functional half-life and ensuring it reaches the tissues where it is needed to stabilize mast cells

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