HCA Healthcare, one of the largest US health systems, told employees it wouldnt keep covering weight loss drugs Zepbound and Wegovy this year , citing a 90% increase in 2025 costs from GLP-1 obesity medications, per STAT
The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis
Abdominal pain warrants careful clinical evaluation to exclude alternative etiologies, irrespective of GLP-1 RA use
Individuals with type 1 diabetes, thyroid cancer, multiple endocrine neoplasia, or end stage kidney disease at any time until cohort entry or individuals with dialysis or the latest eGFR 70 years, by males versus females, by insulin use, by atherosclerotic cardiovascular disease (i.e., myocardial infraction, angina, coronary artery disease, coronary revascularization, peripheral artery disease, aortic atherosclerotic disease, or cerebrovascular disease), by renal insufficiency (i.e., chronic kidney disease or the latest eGFR 70 years (HR [95% CI]: 0.95 [0.831.08])
[6] Its even been noted to have antimicrobial properties and can disrupt bacteria or parasites (for instance, it was used historically to treat malaria)