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Conversely, the deletion of the GPX4 gene in dopaminergic neurons increased anxiety behaviors (Nisar et al., 2023) and promoting N-methyl-D-aspartate (NMDA) receptor-mediated synaptic inhibition in the basolateral amygdala (BLA) (Wu et al., 2022)

There is a limited amount of evidence that it could help reduce muscle soreness as well as decrease post-workout fatigue, or aid immune processes in the aftermath of intense training

Additionally, IGF-1 indirectly improves insulin sensitivity by suppressing growth hormone (GH) secretion through negative feedback mechanisms

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