Comparison of adverse reactions between semaglutide combined with metformin and metformin alone cohorts As shown in Figure 9, the results of adverse reactions, such as hypoglycemia, gastrointestinal reactions and dizziness and headache, between the two groups had no significant difference (SMD=1.58, 95% CI=[0.47, 5.25], P=0.736
A 2025 nutrition review on GLP-1-based therapies highlights practical nutrition priorities during GLP-1 treatment, including attention to protein, fiber, hydration, and overall diet quality
Protein is not optional on semaglutide
Patients should always seek medical advice before starting-GLP-1 medications, as these medications may cause adverse side effects
GLP-1 receptor agonists are synthetic versions of the naturally occurring hormone glucagon-like peptide-1