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With respect to limitations, although the study was sufficiently powered to detect significant effects, the sample was small, limited to females, and predominantly White and non-Hispanic, which restricts the generalizability of the findings

"Effects of doxorubicin-containing chemotherapy and a combination with L-carnitine on oxidative metabolism in patients with non-Hodgkin lymphoma." J Cancer Res Clin Oncol 132(2): 121-128

The included trials show a low risk of selection bias due to the random allocation of participants to the different groups [172]

John AR, Canaday DH

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