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Reta Retatrutide is a novel synthetic peptide that acts as a triple agonist at the glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), and glucagon receptors
Additionally, conflicting findings suggest that prolonged metformin treatment may exacerbate AD pathology in genetically susceptible models, increasing -amyloid accumulation, tau phosphorylation, and synaptic dysfunction 92
Marx N, Federici M, Schtt K et al (2023) 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes
