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elevated levels of autoantibodies and an increased expression of human leukocyte antigen (HLA) class II molecules on biliary epithelial cells have been observed
[1] [2] The slowed transit time through the digestive system means that stool remains in the colon for extended periods, allowing more water to be absorbed and resulting in harder, more difficult-to-pass stools
See efficacy data for IMCIVREE across age groups
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Jastreboff, et al., 'Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA', Lancet , vol
