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For patients with well-controlled hypothyroidism starting semaglutide, baseline TSH measurement provides a reference point for future comparisons

What happened next is the crux of the modern confusion: the compound did not disappear, it migrated into the research-chemical and performance-enhancement markets, where it is discussed as though the early surrogate-marker data were equivalent to proof of a clinical benefit

Trends Endocrinol Amp Metab (2020) 31:41021

Pharmaceutical marketing strategies often attempt to minimize the negative impacts of a drug while exaggerating its advantages

Indeed, yet another review of 37 trials involving 9,341 adults discovered that weight regain after discontinuing weight-loss medications averages 0.4 kg per month, a steady and not slow rate