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The novel anti-cancer fluoropyrimidine NUC-3373 is a potent inhibitor of thymidylate synthase and an effective DNA-damaging agent

While traditional approaches may fall short, innovative scientific advancements offer new pathways

OFA chairman Lee Rosebush says the removal of tirzepatide from the shortage list came without proper federal notice, at a time when the FDA acknowledged shortages still existed

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Note additionally that the three methionine residues in the sequence, two of them in the N-terminal extension, make dilute standing solution vulnerable to oxidation, and that freeze-thaw cycling promotes aggregation in disulfide-bonded proteins more readily than in short peptides