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Gaps in Clinical Knowledge Several critical knowledge gaps impede evidence-based clinical application of BPC-157

(PubMed) Barberger-Gateau P, Letenneur L, Deschamps V, Peres K, Dartigues JF, Renaud S

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ACE2 enzyme degrades ANG II, the major effector of the RAAS that increases hypertension (by lowering baroreceptor sensitivity) to control heart rate, up-regulate vasoconstriction, sodium retention, OxS, inflammation, and fibrosis 300