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GFP signals within the inner autophagosome membrane are degraded in the autolysosomes but mRFP signals are relatively stable and thus provide a visible measure of autophagic flux status 33

Evidence that the enzymes themselves can be modified by redox-related processes such as S -nitrosylation (Romero-Puertas and Sandalio 2016), in addition to the transcriptional control of the genes encoding them, emphasizes the intricacy of the checks and balances operating to maintain redox homeostasis within the cellular environment

Written by Elizabeth Tito, BSc Genetics, MPH Elizabeth is a science and medical writer with a background in Genetics and Public Health

Epub 2017 Aug 7

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