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Consequently, Nrf2 activators have been proposed as antioxidant targets in neurodegenerative and neuropsychiatric disorders (Alzheimers disease, Parkinsons disease, Huntingtons disease, autism, schizophrenia, and depression) to counteract the increase in oxidative stress [138,139,140]

Some formulations also carry indications for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

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It immediately identifies the weak link: the gut barrier and the systemic bioavailability of probiotic-derived GLP-1 remain poorly understood in humans

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