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In a range of animal models of AD or PD, these dual agonists were more effective than exendin-4, liraglutide, semaglutide, or tirzepatide [130, 136, 177, 212,213,214]
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PlexusDx's GLP-Squared dual-compound injection ($289/mo flat for semaglutide + tirzepatide blend) represents another evidence-informed option for patients whose genetics or previous medication trials suggest benefit from simultaneous GLP-1 and GIP pathway activationa medically sound combination unlike phentermine plus GLP-1
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