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With a chronic autoimmune condition like pernicious anaemia many of us have found that we have to advocate for ourselves so understanding the guideline is important for the patient as well as the doctor and our mission is to ensure we improve communication and ultimately improve the guideline as we build on research in the future

Older age : Due to changes in dietary nutrient intake (usually from eating less overall) and also decreased production of stomach acid, the elderly tend to have reduced levels of vitamin B12

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Some individuals report feeling overstimulated with high-dose supplementation, though these reports are anecdotal and not supported by controlled studies