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In the future, BBB models might consider to simulate interactions with the cerebrospinal fluid compartment and with the microbiotagutbrain axis (MGBA)

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Curr Opin Plant Biol 1:258266 Dixon DP, Davis BG, Edwards R (2002) Functional divergence in the glutathione transferase superfamily in plantsidentification of two classes with putative functions in redox homeostasis in Arabidopsis thaliana

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59 Modulation of chromatin looping by the co-activators Prior to the emergence of topological associating domains (TADs), the precise control of transcriptional activation relies on the interaction between remote cis-regulatory modules (e.g., enhancers, and the promoter

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