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Laboratory evaluation typically shows elevated TSH, low free thyroxine (fT4), and increased TPOAb titers, while thyroid ultrasound reveals diffuse hypoechogenicity and heterogeneous parenchymal texture

The Overlapping Biology of Addiction and Obesity Research shows SUDs share biological and psychological similarities with overeating and obesity, with both involving dysregulation of the brains reward system (Srinivasan et al., 2025)

Both types of hypogonadism can impact sperm count and cause other abnormalities in semen resulting in compromised fertility

10.1038/s41569-019-0247-5 81 JenkinsF

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