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394 P2Y6R, which also belongs to the purinergic receptor family, is involved in inflammatory responses and immune regulation by regulating the signaling of extracellular nucleotides (e.g., UDPs) and effectively ameliorates the effects of DSS-induced ulcerative colitis in mice

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This was thought related to the rapid glucose lowering in patients with pre-existing diabetic retinopathy (a known phenomenon where quick improvement of blood sugar can transiently worsen retinopathy)

This orexigenic effect is significantly more pronounced than that of ipamorelin or GHRP-2