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Among the substrates of DPP4 are peptide hormones such as type natriuretic peptides, neuropeptide Y, peptide YY and stromal cell derived factor 1 alpha

The new products are set to be launched at a third to a fifth of the cost of the innovator drug and are already being called generic Ozempic and generic Wegovy. With pharma majors like Dr Reddys, Zydus, Sun Pharmaceuticals, Cipla and Lupin in the fray, the monthly cost of the once-a-week semaglutide injectable is likely to come down to anything between Rs 3,000 and Rs 4,000

H3K4 methylation regulates LPS-induced proinflammatory cytokine expression and release in macrophages

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