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Most people were not familiar with them until the attention they received because of the role they played in countering shortages of GLP-1 medications like Wegovy and Zepbound

conducted an RCT to investigate the prophylactic effects of lycopene against indomethacin-induced gastric ulcer in rats (Boyacioglu et al., 2016).The results showed that pre-administration of lycopene could protect against DNA damage induced by indomethacin, possibly by improving the superoxide dismutase (SOD) activity, glutathione (GSH) level and decreasing catalse (CAT) activity, malondialdehyde (MDA) level and myeloperoxidase (MPO) activity, thus exerting its antioxidative effects

Addressing these determinants requires targeted interventions

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Each operates differently, each is contested by different stakeholders, and each is the subject of separate legislative reform proposals