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Your BMI is 30 or higher, and you have diastolic heart failure, high blood pressure, chronic kidney disease, prediabetes, a previous heart attack or stroke or peripheral artery disease

Late-stage MASLD can also result in hepatocellular carcinoma (HCC), which is a serious health condition

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However, Metformin may not have a clear beneficial effect on -cell preservation during puberty in children and adolescents with obesity and normoglycemia