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Similarly, ROS also activate the mitogen-activated protein kinase (MAPK) cascade, which itself phosphorylates various downstream targets required for cellular defence

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

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Beyond detoxification, glutathione serves critical functions in maintaining cellular redox balance, regulating inflammatory responses, supporting mitochondrial function and energy production, protecting against DNA mutations, and maintaining immune cell function

Int J Neurosci