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[DOI] [PMC free article] [PubMed] [Google Scholar] Sevilla F, Mart MC, De Brasi-Velasco S, Jimnez A

Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron-mediated hydrogen peroxide toxicity

Melanie Avalon: Yes

Cardiac-specific elision of Fth1 (encoding ferritin heavy chain) causes iron dysregulation and increased oxidative stress in the heart, leading to increased sensitivity to ferroptosis induced by iron overload [76]

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