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Back The Economist (24 Oct 2024) 'GLP-1s like Ozempic are among the most important drug breakthroughs ever'

Most studies have been conducted in animal models or small human trials with high risk of bias, and findings often lack replication in larger, well-controlled clinical studies

Depression, anxiety, fatigue, sleep disturbance, and stigma exhibited a U-shaped trajectory, initially improving but subsequently worsening

The STEP 1 extension study found that participants who stopped semaglutide regained approximately two-thirds of their previously lost weight within one year

Evaluating the Efficacy and Safety of Long-Acting GLP-1 Receptor Agonists in T1DM Patients. Endocrines , vol