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[141] Although there have been sporadic synthetic efforts since 1972, [140] the EschenmoserWoodward synthesis remains the only completed (formal) total synthesis
Both types are used based on whats best for each patient
[127] [128] Synthesis [edit] Biosynthesis [edit] Vitamin B 12 is derived from a tetrapyrrolic structural framework created by the enzymes deaminase and cosynthetase which transform aminolevulinic acid via porphobilinogen and hydroxymethylbilane to uroporphyrinogen III
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