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Therapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: a paradigm shift

BenHur, N

Updated: March, 13 2026 In late 2023, the Food and Drug Administration (FDA) removed 19 peptides from their FDA Category 1 list to FDA Category 2

In one phase 2 trial of people with obesity, some of whom also had type 2 diabetes, participants lost 20.5% of their fat mass while increasin g their lean muscle mass by 3.6% over 48 weeks of treatment

Anyone planning research-context use should treat outcome reports cautiously and weigh the FDA-approved alternatives discussed in the comparisons section