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doi: 10.3389/fphar.2020.00189 Received 23 September 2019 Accepted 10 February 2020 Published 04 March 2020 Volume 11 - 2020 Edited by Sabina Passamonti, University of Trieste, Italy Reviewed by Xiaoli Meng, University of Liverpool, United Kingdom

France permits peptides only for clinical trials and research

Risk Summary There is no information regarding the presence of ADVATE in human milk, the effect on the breastfed infant, or the effects on milk production

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This review synthesizes peer-reviewed evidence available from 20202026, focusing on observed mechanisms, reported efficacy, and safety considerations