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Concurrently, polyphenolic compounds can exert neuroprotective effects by regulating adult neurogenesis, synaptogenesis, and neuroplasticity, as well as the activation of microglia ( 4 Mechanisms underlying the effect of antioxidants on neuropsychiatric disorders The mechanisms through which antioxidants impact neuropsychiatric disorders can be summarized into several key areas: neuroprotection, synaptic regulation, modulation of microglial activity, and neurotrophic effects (as depicted in Figure 2)

A decline in body weight was detected in the first week after surgery due to OA-induced pain (Supplementary Fig

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Coord Chem Rev 184:311318 Ba LA, Doering M, Burkholz T, Jacob C (2009) Metal trafficking: from maintaining the metal homeostasis to future drug design