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8 weeks) in C57BL/6 produces pericentral HSC activation, collagen I/III deposition (Sirius Red staining), and biochemical hepatitis (ALT, AST elevation)

Mixed inflammatory cholangitis represents a therapeutic challenge because the treatment of neutrophilic and lymphocytic cholangitis is contradictory

Choline is absolutely required for VLDL assembly and secretion

This pairs well with compounds that create pulses, like GH secretagogues, as the IGF-1 LR3 is active throughout multiple GH pulses

(A) Lichen striatus in a child with flat skin-colored papules arranged linearly on the dorsum of the first finger, associated with nail plate onychorrhexis