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These include pancreatitis (inflammation of the pancreas), kidney problems, and allergic reactions

Dehydration and low blood sugar are the most likely culprits

Reactivation of latent viral pathogens Since the onset of COVID-19 pandemic, a strong correlation between SARS-CoV-2 infection or COVID-19 vaccination and herpesvirus co-infection/reactivation has been reported 255

When the formulation includes B6, the pyridoxine is typically already incorporated into the lyophilized powder or provided as a pre-mixed solution

Additionally, receptor expression may dynamically change during treatment (e.g., upregulation or downregulation in response to therapy), further impacting the long-term reliability of active targeting NPs