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Free haemoglobin concentration in the perfusate gradually increased over time (mean rate 0.05 0.08 g/L/h, n = 34, Supplementary Information, Fig

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Some studies suggest that combining oral and topical glutathione can provide better brightening results than using either method alone. Certain formulations, such as liposomal or acetylated glutathione, are designed to improve stability and absorption, but clinical outcomes may differ between products